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KMID : 1195020230190010135
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Archives of Orthopedic and Sports Physical Therapy
2023 Volume.19 No. 1 p.135 ~ p.142
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Osteoporosis Management: A Study on the Synergistic Effects of Medication Treatment and Resistance Exercise
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Yoon Ui-Yeol
Kim Yu-Shin
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Abstract
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Purpose: The prevalence of osteoporosis is 34.9% and 7.4% in women and men, respectively. It is reportedin 1 in 5 middle-aged and postmenopausal women in Korea. In osteoporosis, an imbalance betweenosteoblasts and osteoclasts leads to reduced bone density, resulting in weakened bones and an increasedrisk of fractures. The T-Score is an index to assess bone density, representing the standard deviation in bonedensity compared to that of young adults. A T-score of -1.0 or higher is considered normal, -1.0 to -2.5indicates osteopenia or low bone density, and -2.5 or less indicates osteoporosis.
Methods: Patients with a history of femoral or vertebral fractures or osteoporosis, after excluding secondarycauses, were eligible for drug therapy. Drug therapy for osteoporosis includes bisphosphonate preparations,female hormone therapy (estrogen), selective estrogen modulators, teriparatide (parathyroid hormone),denosumab, and alendronate. Exercise is widely recommended as it is reported to prevent bone loss, increasebone strength, and mitigate muscle loss, muscle weakness, and balance problems due to aging.
Results: Exercise effectively prevents osteoporosis by improving bone density and functions of the muscularand nervous systems. Exercises that apply physical stress to the bone tissue, such as resistance exercisesand weight training, are recommended treating osteoporosis.
Conclusion: These exercises not only lower the rate of bone density loss but also increase bone density.
Therefore, this study aimed to present a theoretical basis for effective management to improve bone densityin patients with osteoporosis.
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KEYWORD
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Osteoporosis, Bisphosphonate, Denosumap, Terapiratide, Resistance exercises
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